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Patient is a 16 year-old male chronic parenteral nutrition dependence secondary to short bowel syndrome secondary to atresia. Despite several intestinal lengthening procedures at your center, he continues to receive the vast majority of his nutrition intravenously. Family complains that frequent in...

Family notices there is something unusual about the appearance of their child’s central line (see photo below). The line is functioning fine. There is no leaking. The patient is asymptomatic. What is the problem? A. Outer lumen fracture B. Inner lumen fracture C. Central line thrombus D. Central...

During a dressing change, the parents note the central line exit site looks different (see photo below). What is the problem? A. Central venous catheter cuff exposed B. Cellulitis at central line exit site C. Eczema at central venous catheter exit site D. Central line exit-site and tunnel infection...

During a dressing change, the parents note the central line exit site looks different (see photo below). What is the problem? A. Central venous catheter cuff exposed B. Cellulitis at central line exit site C. Eczema at central venous catheter exit site D. Central line exit-site and tunnel infection...

A 25 year-old patient with a Port-a-Cath implanted in the right chest complains of sudden onset severe neck pain and headaches with flushing central line and PN infusions. Labs and exam normal, including afebrile. Previous X-ray shows central line tip in at the cavo-atrial junction. Today, chest X...

Appreciate the contributions of the following and others to the website's content: Alexandra Carey, MD Daniel Kamin, MD Jennifer McClelland, FNP-BC Carolyn Rosa, CPNP-BC Mary Gallotto, BSN Melissa Takvorian-Bene, BSN Megan Gray, RD Ana Arena, RD Christina Tascione, BA Kathleen Gura, PharmD Margaret...

Overview Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases. We have three main areas: (1) vascular tumors (infantile hemangioma) and (2)vascular malformations (e.g., capillary malformation), (3) endothelial to mesenchymal transition (EndMT) in...

We study endothelial plasticity in cardiac valves and how this relates to the ability of valves to adapt to both normal and pathologic events. We showed that valve endothelial cells (VECs) from aortic, pulmonic and mitral valves can recapitulate processes that occur during valve development - e.g...

Joyce Bischoff, PhD Principle Investigator Joyce Bischoff received an A.B. in chemistry from Duke University and a Ph.D. in biochemistry from the Washington University School of Medicine. She was a post-doctoral fellow at the Whitehead Institute for Biomedical Research. She joined the Surgical...