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TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.
Chen, Maorong, Nathalia Amado, Jieqiong Tan, Alice Reis, Mengxu Ge, Jose Garcia Abreu, and Xi He. 2020. “TMEM79/MATTRIN Defines a Pathway for Frizzled Regulation and Is Required for Xenopus Embryogenesis.”. ELife 9.
An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity.
Xu, Chiwei, Brian Franklin, Hong-Wen Tang, Yannik Regimbald-Dumas, Yanhui Hu, Justine Ramos, Justin A Bosch, Christians Villalta, Xi He, and Norbert Perrimon. 2020. “An in Vivo RNAi Screen Uncovers the Role of AdoR Signaling and Adenosine Deaminase in Controlling Intestinal Stem Cell Activity.”. Proceedings of the National Academy of Sciences of the United States of America 117 (1): 464-71.
APC Deficiency Leads to β-Catenin Stabilization and Signaling Independent of LRP5/6.
Chen, Maorong, and Xi He. 2019. “APC Deficiency Leads to β-Catenin Stabilization and Signaling Independent of LRP5/6.”. Developmental Cell 49 (6): 825-26.
Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B.
Chen, Peng, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-Ho Lam, Zheng Liu, et al. 2018. “Structural Basis for Recognition of Frizzled Proteins by Clostridium Difficile Toxin B.”. Science (New York, N.Y.) 360 (6389): 664-69.
Methods for Studying Wnt Protein Modifications/Inactivations by Extracellular Enzymes, Tiki and Notum.
Zhang, Xinjun, and Xi He. 2016. “Methods for Studying Wnt Protein Modifications/Inactivations by Extracellular Enzymes, Tiki and Notum.”. Methods in Molecular Biology (Clifton, N.J.) 1481: 29-38.
Characterization of Tiki, a New Family of Wnt-specific Metalloproteases.
Zhang, Xinjun, Bryan T MacDonald, Huilan Gao, Michael Shamashkin, Anthony J Coyle, Robert Martinez V, and Xi He. 2016. “Characterization of Tiki, a New Family of Wnt-Specific Metalloproteases.”. The Journal of Biological Chemistry 291 (5): 2435-43.
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.
Wang, Lili, Alex K Shalek, Mike Lawrence, Ruihua Ding, Jellert T Gaublomme, Nathalie Pochet, Petar Stojanov, et al. 2014. “Somatic Mutation As a Mechanism of Wnt/β-Catenin Pathway Activation in CLL.”. Blood 124 (7): 1089-98.
FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.
Uchihashi, Kazuyoshi, Teruyo Nakatani, Regina Goetz, Moosa Mohammadi, Xi He, and Mohammed S Razzaque. 2013. “FGF23-Induced Hypophosphatemia Persists in Hyp Mice Deficient in the WNT Coreceptor Lrp6.”. Contributions to Nephrology 180: 124-37.
Wnt signalling: What The X@# is WTX?
Regimbald-Dumas, Yannik, and Xi He. 2011. “Wnt Signalling: What The X@# Is WTX?”. The EMBO Journal 30 (8): 1415-7.