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APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons

Publication: Journal Article

Wu, Chun-I, Elizabeth A Vinton, Richard Pearse V, Keunjung Heo, Aimee J Aylward, Yi-Chen Hsieh, Yan Bi, et al. 2022. “APP and DYRK1A Regulate Axonal and Synaptic Vesicle Protein Networks and Mediate Alzheimer’s Pathology in Trisomy 21 Neurons”. Molecular Psychiatry 27 (4): 1970-89.

Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria

Publication: Journal Article

Heo, Keunjung, Himanish Basu, Amos Gutnick, Wei Wei, Evgeny Shlevkov, and Thomas L. Schwarz. 2022. “Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria”. Frontiers in Cellular Neuroscience 16.

FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply

Publication: Journal Article

Basu, Himanish, Gulcin Pekkurnaz, Jill Falk, Wei Wei, Morven Chin, Judith Steen, and Thomas L Schwarz. 2021. “FHL2 Anchors Mitochondria to Actin and Adapts Mitochondrial Dynamics to Glucose Supply”. Journal of Cell Biology 220 (10): e201912077.

Ingo Fohmann

Person: Research Fellow, Vascular Biology Program, Boston Children's Hospital, Research Fellow, Harvard Medical School

Ingo received his PhD from the Institute for Hygiene and Microbiology in Würzburg, Germany. During his PhD project he was interested in the function of sphingolipids in the brain endothelium during infection with the bacterial pathogen Neisseria meningitidis. He discovered that the infection leads...

Deep Learning-Based Visual Complexity Analysis of Electroencephalography Time-Frequency Images: Can It Localize the Epileptogenic Zone in the Brain?

Publication: Journal Article

Makaram, Navaneethakrishna, Sarvagya Gupta, Matthew Pesce, Jeffrey Bolton, Scellig Stone, Daniel Haehn, Marc Pomplun, et al. 2023. “Deep Learning-Based Visual Complexity Analysis of Electroencephalography Time-Frequency Images: Can It Localize the Epileptogenic Zone in the Brain?”. Algorithms 16 (12).

Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.

Publication: Journal Article

Pfau, Sarah J, Urs H Langen, Theodore M Fisher, Indumathi Prakash, Faheem Nagpurwala, Ricardo A Lozoya, Wei-Chung Allen Lee, Zhuhao Wu, and Chenghua Gu. 2024. “Characteristics of Blood-Brain Barrier Heterogeneity Between Brain Regions Revealed by Profiling Vascular and Perivascular Cells.”. Nature Neuroscience 27 (10): 1892-1903.

November 2024 Publications by DON Faculty

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A Cancer Center Multidisciplinary Lifestyle Medicine Clinic: Description of Program and Patient Population. Millstein RA, Lee H, Lapioli A, Winters L, Sullivan C, Bateman S, Frates E, Comander A, Eisenstat S, Peppercorn J, O'Donnell EK. Am J Lifestyle Med. 2023 Oct 17;18(6):791-801. doi: 10.1177...

A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity

Publication: Journal Article

Cartoni, Romain, Gulcin Pekkurnaz, Chen Wang, Thomas L. Schwarz, and Zhigang He. 2017. “A High Mitochondrial Transport Rate Characterizes CNS Neurons With High Axonal Regeneration Capacity”. PLOS ONE 12 (9): 1-12.

Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons.

Publication: Journal Article

Ott, Carolyn M, Sandii Constable, Tri M Nguyen, Kevin White, Wei-Chung Allen Lee, Jennifer Lippincott-Schwartz, and Saikat Mukhopadhyay. 2024. “Permanent Deconstruction of Intracellular Primary Cilia in Differentiating Granule Cell Neurons.”. The Journal of Cell Biology 223 (10).

Synaptic architecture of leg and wing premotor control networks in Drosophila.

Publication: Journal Article

Lesser, Ellen, Anthony W Azevedo, Jasper S Phelps, Leila Elabbady, Andrew Cook, Durafshan Sakeena Syed, Brandon Mark, et al. 2024. “Synaptic Architecture of Leg and Wing Premotor Control Networks in Drosophila.”. Nature 631 (8020): 369-77.