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A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.

Publication: Journal Article

Vaidyanathan, Kalyanaraman, Chuangqi Wang, Amanda Krajnik, Yudong Yu, Moses Choi, Bolun Lin, Junbong Jang, et al. 2021. “A Machine Learning Pipeline Revealing Heterogeneous Responses to Drug Perturbations on Vascular Smooth Muscle Cell Spheroid Morphology and Formation.”. Scientific Reports 11 (1): 23285.

Caitlin Bowen, MD, PhD

she/her

Person: Pediatric Cardiology Fellow

Dr. Caitlin Bowen is a Pediatric Cardiology Fellow at Boston Children’s Hospital. Dr. Bowen obtained her MD/PhD degrees through the Medical Scientist Training Program at Johns Hopkins University School of Medicine, after attending Cornell University and a fellowship at the National Institutes of...

Aryn Lee

she/her

Person: Clinical Research Assistant

Aryn Lee is a Clinical Research Assistant working for Dr. Esra Abaci Turk’s team on fetal and placental MRI. She graduated from Boston University in 2025 with a BA in Psychology. Prior to this role, Aryn was a Graduate Research Intern at FNNDSC with Dr. Sarah Morton, and continues to investigate...

Ion transport and channel transition in biomembranes

Publication: Journal Article

Lee, Kwonmoo, and Wokyung Sung. 2002. “Ion Transport and Channel Transition in Biomembranes”. Physica A: Statistical Mechanics and Its Applications 315 (1): 79-97.

A Stochastic Model of Conductance Transitions in Voltage-Gated IonChannels

Publication: Journal Article

Lee, Kwonmoo, and Wokyung Sung. 2002. “A Stochastic Model of Conductance Transitions in Voltage-Gated IonChannels”. Journal of Biological Physics 28 (2): 279-88.

Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.

Publication: Journal Article

Lee, Kwonmoo, Hunter L Elliott, Youbean Oak, Chih-Te Zee, Alex Groisman, Jessica D Tytell, and Gaudenz Danuser. 2015. “Functional Hierarchy of Redundant Actin Assembly Factors Revealed by Fine-Grained Registration of Intrinsic Image Fluctuations.”. Cell Systems 1 (1): 37-50.

Emerging machine learning approaches to phenotyping cellular motility and morphodynamics

Publication: Journal Article

Choi, Hee June, Chuangqi Wang, Xiang Pan, Junbong Jang, Mengzhi Cao, Joseph A Brazzo, Yongho Bae, and Kwonmoo Lee. 2021. “Emerging Machine Learning Approaches to Phenotyping Cellular Motility and Morphodynamics”. Physical Biology 18 (4): 041001.

Deep cross-modal feature learning applied to predict acutely decompensated heart failure using in-home collected electrocardiography and transthoracic bioimpedance.

Publication: Journal Article

Pan, Xiang, Chuangqi Wang, Yudong Yu, Natasa Reljin, David D McManus, Chad E Darling, Ki H Chon, Yitzhak Mendelson, and Kwonmoo Lee. 2023. “Deep Cross-Modal Feature Learning Applied to Predict Acutely Decompensated Heart Failure Using In-Home Collected Electrocardiography and Transthoracic Bioimpedance.”. Artificial Intelligence in Medicine 140: 102548.

Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells.

Publication: Journal Article

Krajnik, Amanda, Erik Nimmer, Joseph A Brazzo, John C Biber, Rhonda Drewes, Bat-Ider Tumenbayar, Andra Sullivan, et al. 2023. “Survivin Regulates Intracellular Stiffness and Extracellular Matrix Production in Vascular Smooth Muscle Cells.”. APL Bioengineering 7 (4): 046104.

Breast Cancer-Derived Extracellular Vesicles Modulate the Cytoplasmic and Cytoskeletal Dynamics of Blood-Brain Barrier Endothelial Cells.

Publication: Journal Article

Busatto, Sara, Tzu-Hsi Song, Hyung Joon Kim, Caleb Hallinan, Michael N Lombardo, Anat O Stemmer-Rachamimov, Kwonmoo Lee, and Marsha A Moses. 2025. “Breast Cancer-Derived Extracellular Vesicles Modulate the Cytoplasmic and Cytoskeletal Dynamics of Blood-Brain Barrier Endothelial Cells.”. Journal of Extracellular Vesicles 14 (1): e70038.