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Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain

Publication: Journal Article

C, Ren, Morohashi K, Plotnikov AN, Jakoncic J, Smith SG, Li J, Zeng L, et al. 2015. “Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain”. Chemistry & Biology 2 (22): 161-68.

Publication: Journal Article

Publication: Journal Article

F, Zhang, Ren C, Lau KK, Zheng Z, Lu G, Yi Z, Zhao Y, et al. 2016. “A Network Medicine Approach to Build a Comprehensive Atlas for the Prognosis of Human Cancer”. Briefings in Bioinformatics 17 (6): 1044-59.

Publication: Journal Article

T, Konuma, Yu D, Zhao C, Ju Y, Sharma R, Ren C, Zhang Q, Zhou MM, and Zeng L. 2017. “Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4”. Scientific Reportsvolume 7 (16272).

Publication: Journal Article

F*, Zhang, Zhao S*, Ren C*, Zhu Y, Zhou H, Lai Y, Zhou F, Jia Y, Zheng K, and Huang Z. 2018. “CRISPRminer Is a Knowledge Base for Exploring CRISPR-Cas Systems in Microbe and Phage Interactions”. Communications Biology 1 (180).

Publication: Journal Article

C*, Ren, Smith SG*, Yap KL, Li S, Li J, Mezei M, Vincek AS, Aguilo F, Walsh MJ, and Zhou MM. 2016. “Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7”. ACS Medicinal Chemistry Letters 7 (6): 601-5.

Publication: Journal Article

Publication: Journal Article

KL, Cheung, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, et al. 2017. “Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation”. Molecular Cell 65 (6): 1068-1080.e5.

Publication: Journal Article

C*, Ren, Zhang G*, Han F, Fu S, Cao Y, Zhang F, Zhang Q, et al. 2018. “Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth”. Proceedings of the National Academy of Sciences of the United States of America 115 (31): 7949-54.

Publication: Journal Article