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Infantile hemangioma is a vascular tumor that can grow rapidly, causing organ damage, disfigurement and morbidity. My lab has focused on the cellular mechanisms that drive this uncontrolled vascular growth. We isolated increasingly less differentiated cells from hemangioma tissue (see figure), which...

Energy, Fluid, Acid-Base & Electrolyte Management Dextrose Amino Acids Lipids Micronutrient monitoring & disorders Iron deficiency anemia (including intravenous iron)

Patient is 13 year-old female unable to tolerate any enteral intake due to chronic small bowel obstruction and a history of heavy menses. For past 6 months, she complains of worsening fatigue and pallor. Hemaglobin is 8 (low), MCV 66 (low and previously normal). On exam, there is no tachycardia...

2 year-old male had a recent adjustment in parenteral nutrition infusion cycle from 18 to 12 hours. There was no change in PN concentration. As a result, the glucose of infusion rate changed from 14 to 25 mg/kg/minute. Mother calls to complain that has symptoms of polydipsia and dehydration during...

The parent of an 8 year-old female with chronic parenteral nutrition dependence secondary to chronic intestinal pseudo-obstruction calls with leaking at right upper extremity peripherally inserted central catheter (PICC) within 2 hours of nightly infusion. What is the first thing to recommend to...

5 year-old female with HPN dependence secondary to meconium pseudo-cyst develops acute agitation, headaches and vomiting immediately upon infusing HPN, which is a new batch from that was delivered yesterday. Of note, there have been no recent HPN prescription changes. Patient lives with parents in a...

Patient is a 16 year-old male chronic parenteral nutrition dependence secondary to short bowel syndrome secondary to atresia. Despite several intestinal lengthening procedures at your center, he continues to receive the vast majority of his nutrition intravenously. Family complains that frequent in...

Family notices there is something unusual about the appearance of their child’s central line (see photo below). The line is functioning fine. There is no leaking. The patient is asymptomatic. What is the problem? A. Outer lumen fracture B. Inner lumen fracture C. Central line thrombus D. Central...

During a dressing change, the parents note the central line exit site looks different (see photo below). What is the problem? A. Central venous catheter cuff exposed B. Cellulitis at central line exit site C. Eczema at central venous catheter exit site D. Central line exit-site and tunnel infection...

During a dressing change, the parents note the central line exit site looks different (see photo below). What is the problem? A. Central venous catheter cuff exposed B. Cellulitis at central line exit site C. Eczema at central venous catheter exit site D. Central line exit-site and tunnel infection...