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Li Chao

Person: Research Fellow, Vascular Biology Program, Boston Children's Hospital, Research Fellow, Harvard Medical School
Chao completed his PhD in Genetics at Fudan University in 2022, where his research primarily focused on the mechanisms by which noncoding RNAs contribute to the development of congenital heart diseases. This work paved the way for his interest in molecular biology and gene regulation within...

Contributions to Science

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1. My laboratory discovered the G protein-coupled receptor for sphingosine 1-phosphate (S1P) in the 1990s. At that time, S1P was widely considered as an intracellular second messenger. We cloned EDG-1 as an angiogenesis-inducible G protein-coupled receptor (GPCR) in 1990 and “de-orphaned” it as the...

Tim Dorweiler

Person: Research Fellow, Vascular Biology Program, Boston Children's Hospital, Research Fellow, Harvard Medical School
Tim earned his BS from Heinrich-Heine University in Duesseldorf (Germany) in association with Michigan State University (USA). His thesis described a potential mechanism of how dextromethorphan derived anti-diabetics promote insulin secretion. Subsequently, he acquired his MS at the German Diabetes...

Ingo Fohmann

Person: Research Fellow, Vascular Biology Program, Boston Children's Hospital, Research Fellow, Harvard Medical School
Ingo received his PhD from the Institute for Hygiene and Microbiology in Würzburg, Germany. During his PhD project he was interested in the function of sphingolipids in the brain endothelium during infection with the bacterial pathogen Neisseria meningitidis. He discovered that the infection leads...

News and Events

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A BIG shoutout to Chao Li and Tim Dorweiler, AHA grant awardees ! Congrats and best wishes to Dairo (with Hla lab summer kids, Arlette and Emil)! Congratulations to Andrew Kuo on his publication! Kuo A, Hla T. Regulation of cellular and systemic sphingolipid homeostasis. Nat Rev Mol Cell Biol. 2024...