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Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract that has a prevalence of over 800,000 in the US alone, primarily affecting young individuals. The disease's characteristic periods of remission and relapse necessitate frequent hospitalizations. There has been a...

Functional imaging with dynamic contrast-enhanced MRI (DCE-MRI) provides physiological markers of permeability, perfusion and glomerular filtration rate (GFR), a measure of kidney function. One of the most important applications of DCE-MRI is to assess GFR in pediatric hydronephrosis patients with...

Ureteropelvic junction obstruction (UPJO) is an impairment of urine flow from the renal pelvis into the proximal ureter and is the most common cause of hydronephrosis in neonates. This disorder is detected in up to 7% of all maternal ultrasound scans, and an estimated 10% of these newborns have...