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FANC Project
Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy To investigate circuit mechanisms underlying locomotor behavior, we used serial-section electron microscopy (EM) to acquire a synapse-resolution dataset containing the ventral nerve cord...
Synaptic architecture of leg and wing premotor control networks in Drosophila.
Lesser, Ellen, Anthony W Azevedo, Jasper S Phelps, Leila Elabbady, Andrew Cook, Durafshan Sakeena Syed, Brandon Mark, et al. 2024. “Synaptic Architecture of Leg and Wing Premotor Control Networks in Drosophila.”. Nature 631 (8020): 369-77.
Ultrastructural differences impact cilia shape and external exposure across cell classes in the visual cortex.
Ott, Carolyn M, Russel Torres, Tung-Sheng Kuan, Aaron Kuan, JoAnn Buchanan, Leila Elabbady, Sharmishtaa Seshamani, et al. 2024. “Ultrastructural Differences Impact Cilia Shape and External Exposure across Cell Classes in the Visual Cortex.”. Current Biology : CB 34 (11): 2418-2433.e4.
ADULT DROSOPHILA VNC TEM DATASET - FEMALE ADULT NERVE CORD (FANC)
Associated publication: Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy. Dataset and neuron reconstructions available at: Virtual Fly Brain We manage a collaborative reconstruction community for tracing neurons in the FANC dataset. Please...
Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy
Phelps, Jasper S., David Grant Colburn Hildebrand, Brett J. Graham, Aaron T. Kuan, Logan A. Thomas, Tri Nguyen, Julia Buhmann, et al. 2021. “Reconstruction of Motor Control Circuits in Adult Drosophila Using Automated Transmission Electron Microscopy”. Cell 184 (3): 759–774.
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism
Cheadle, Lucas, Samuel A. Rivera, Jasper S. Phelps, Katelin A. Ennis, Beth Stevens, Linda C. Burkly, Wei-Chung Allen Lee, and Michael E. Greenberg. 2020. “Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism”. Neuron 108 (3): 451-468.E9.
Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.
Zhang, Qiyu, Wei-Chung Lee, David Paul, and David Ginty. 2019. “Multiplexed Peroxidase-Based Electron Microscopy Labeling Enables Simultaneous Visualization of Multiple Cell Types.”. Nat Neurosci 22: 828–839.
Whole-brain serial-section electron microscopy in larval zebrafish.
Hildebrand, David Grant Colburn, Marcelo Cicconet, Russel Miguel Torres, Woohyuk Choi, Tran Minh Quan, Jungmin Moon, Arthur Willis Wetzel, et al. 2017. “Whole-Brain Serial-Section Electron Microscopy in Larval Zebrafish.”. Nature 545: 345–349.