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Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi

Publication: Journal Article

Ko, Genevieve, Summer Paradise, Hong Chen, Morven Graham, Manuela Vecchi, Fabrizio Bianchi, Ottavio Cremona, Pier Paolo Di Fiore, and Pietro De Camilli. 2010. “Selective High-Level Expression of Epsin 3 in Gastric Parietal Cells, Where It Is Localized at Endocytic Sites of Apical Canaliculi”. Proc Natl Acad Sci U S A 107 (50): 21511-6.

A histone-binding protein, nucleoplasmin, stimulates transcription factor binding to nucleosomes and factor-induced nucleosome disassembly

Publication: Journal Article

Chen, Li, and Workman. 1994. “A Histone-Binding Protein, Nucleoplasmin, Stimulates Transcription Factor Binding to Nucleosomes and Factor-Induced Nucleosome Disassembly”. EMBO J 13 (2): 380-90.

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We study a family of endocytic adaptor proteins called epsins, which are central to a number of important diseases in humans, including atherosclerosis, diabetes, cancer, and obesity. We have developed novel conditional mouse strains that have aided in the detailed characterization of epsins and...