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149 results found

Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase

Publication: Journal Article

Qi, Yihang, Abdol-Hossein Rezaeian, Jingchao Wang, Daoyuan Huang, Hong Chen, Hiroyuki Inuzuka, and Wenyi Wei. 2024. “Molecular Insights and Clinical Implications for the Tumor Suppressor Role of SCFFBXW7 E3 Ubiquitin Ligase”. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1879 (5): 189140.

Editorial: The Role of the Lymphatic System in Lipid and Energy Metabolism, and Immune Homeostasis During Obesity and Diabetes

Publication: Journal Article

Cifarelli, Vincenza, Hong Chen, and Joshua Scallan. 2021. “Editorial: The Role of the Lymphatic System in Lipid and Energy Metabolism, and Immune Homeostasis During Obesity and Diabetes”. Frontiers in Physiology 12: 652461.

Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation

Publication: Journal Article

Brophy, Megan, Yunzhou Dong, Huan Tao, Patricia Yancey, Kai Song, Kun Zhang, Aiyun Wen, et al. 2019. “Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation”. Circulation Research 124 (4).

Hong Chen

Person: Principal Investigator at Boston Children's Hospital, Professor of Surgery at Harvard Medical School

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Professor Hong Chen Vascular Biology Program Boston Children's Hospital Karp Family Research Laboratories Room 12214, Mailstop: 3137 1 Blackfan Street Boston, MA 02115 Contact E-mail

PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy

Publication: Journal Article

Lu, Yao Wei, Zhuomin Liang, Haipeng Guo, Tiago Fernandes, Ramon A Espinoza-Lewis, Tingting Wang, Kathryn Li, et al. 2023. “PCBP1 Regulates Alternative Splicing of AARS2 in Congenital Cardiomyopathy”. BioRxiv 2023.05.18.540420.

Endothelial-derived extracellular microRNA-92a promotes arterial stiffness by regulating phenotype changes of vascular smooth muscle cells

Publication: Journal Article

Wang, Chen, Haoyu Wu, Yuanming Xing, Yulan Ye, Fangzhou He, Qian Yin, Yujin Li, Fenqing Shang, John Y-J Shyy, and Zu-Yi Yuan. 2022. “Endothelial-Derived Extracellular MicroRNA-92a Promotes Arterial Stiffness by Regulating Phenotype Changes of Vascular Smooth Muscle Cells”. Scientific Reports 12 (1): 344.

LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1 AMPK signaling pathway

Publication: Journal Article

Liu, Ning, Masaharu Kataoka, Yingchao Wang, Linbin Pu, Xiaoxuan Dong, Xuyang Fu, Feng Zhang, et al. 2021. “LncRNA LncHrt Preserves Cardiac Metabolic Homeostasis and Heart Function by Modulating the LKB1 AMPK Signaling Pathway”. Basic Research in Cardiology 116 (1): 48.

Endocytic Adaptors in Cardiovascular Disease

Publication: Journal Article

Cui, Kui, Yunzhou Dong, Beibei Wang, Douglas B Cowan, Siu-Lung Chan, John Shyy, and Hong Chen. 2020. “Endocytic Adaptors in Cardiovascular Disease”. Frontiers in Cell and Developmental Biology 8: 624159.

Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development

Publication: Journal Article

Chang, Baojun, Kandice L Tessneer, John McManus, Xiaolei Liu, Scott Hahn, Satish Pasula, Hao Wu, et al. 2015. “Epsin Is Required for Dishevelled Stability and Wnt Signalling Activation in Colon Cancer Development”. Nature Communications 6: 6380.