Mengxu Ge, PhD
Studying the Wnt signaling in the skin. Mengxu.Ge@childrens.harvard.edu
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Danilo Predes, PhD
Studying the Wnt signaling in disease. Danilo.Predes@childrens.harvard.edu
Eunice To, PhD
Studying the Atopic March. Eunice.To@childrens.harvard.edu
Notum Deletion From Late-Stage Skeletal Cells Increases Cortical Bone Formation and Potentiates Skeletal Effects of Sclerostin Inhibition.
Choi, Roy B, Whitney A Bullock, April M Hoggatt, Daniel J Horan, Emily Z Pemberton, Jung Min Hong, Xinjun Zhang, Xi He, and Alexander G Robling. 2021. “Notum Deletion From Late-Stage Skeletal Cells Increases Cortical Bone Formation and Potentiates Skeletal Effects of Sclerostin Inhibition.”. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 36 (12): 2413-25.
Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation.
Ma, Wenzhe, Maorong Chen, Hong Kang, Zachary Steinhart, Stephane Angers, Xi He, and Marc W Kirschner. 2020. “Single-Molecule Dynamics of Dishevelled at the Plasma Membrane and Wnt Pathway Activation.”. Proceedings of the National Academy of Sciences of the United States of America 117 (28): 16690-701.
SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation.
Ci, Yanpeng, Xiaoning Li, Maorong Chen, Jiateng Zhong, Brian J North, Hiroyuki Inuzuka, Xi He, Yu Li, Jianping Guo, and Xiangpeng Dai. 2018. “SCFβ-TRCP E3 Ubiquitin Ligase Targets the Tumor Suppressor ZNRF3 for Ubiquitination and Degradation.”. Protein & Cell 9 (10): 879-89.
Expression and evolution of the Tiki1 and Tiki2 genes in vertebrates.
Reis, Alice H, Bryan Macdonald, Kerstin Feistel, Jose M Brito, Nathalia G Amado, Chiwei Xu, Jose G Abreu, and X I He. 2014. “Expression and Evolution of the Tiki1 and Tiki2 Genes in Vertebrates.”. The International Journal of Developmental Biology 58 (5): 355-62.
Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.
MacDonald, Bryan T, Mikhail Semenov V, He Huang, and Xi He. 2011. “Dissecting Molecular Differences Between Wnt Coreceptors LRP5 and LRP6.”. PloS One 6 (8): e23537.
Wnt signalling: What The X@# is WTX?
Regimbald-Dumas, Yannik, and Xi He. 2011. “Wnt Signalling: What The X@# Is WTX?”. The EMBO Journal 30 (8): 1415-7.
Wnt/beta-catenin signaling: components, mechanisms, and diseases.
MacDonald, Bryan T, Keiko Tamai, and Xi He. 2009. “Wnt/Beta-Catenin Signaling: Components, Mechanisms, and Diseases.”. Developmental Cell 17 (1): 9-26.