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Carter Cummerata

Person: Aspernatur quisquam

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Ready-made CAR T Cells

News: August 04, 2022

New method could allow scaled-up production of generic cells for cancer immunotherapies By NANCY FLIESLER | Boston Children’s August 4, 2022 Research 3 min read Killer T cells (green and red) surround a cancer cell (blue, center). Image: Alex Ritter, Jennifer Lippincott Schwartz, and Gillian...

Ran Jing, Ph.D. - Boston Children's Hospital/Harvard Medical School

Dr. Ran Jing is a stem cell biologist and immunologist at Harvard Medical School and Boston Children's Hospital. Dr. Jing's research focuses on decoding the intricacies of lymphoid development using innovative models like iPSC-derived T and NK cells. Concurrently, we employ cell engineering, regenerative medicine, and synthetic biology to create off-the-shelf CAR T cell immunotherapies for cancer and autoimmune diseases.

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia

Publication: Journal Article

Cayo, M. A., S. K. Mallanna, F. Di Furio, R. Jing, L. B. Tolliver, M. Bures, A. Urick, et al. 2017. “A Drug Screen Using Human IPSC-Derived Hepatocyte-Like Cells Reveals Cardiac Glycosides As a Potential Treatment for Hypercholesterolemia”. Cell Stem Cell 20: 478-489 e5.

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon

Publication: Journal Article

Munera, J. O., D. O. Kechele, C. Bouffi, N. Qu, R. Jing, P. Maity, J. R. Enriquez, et al. 2023. “Development of Functional Resident Macrophages in Human Pluripotent Stem Cell-Derived Colonic Organoids and Human Fetal Colon”. Cell Stem Cell 30: 1434-1451 e9.

FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1

Publication: Journal Article

Twaroski, K., S. K. Mallanna, R. Jing, F. DiFurio, A. Urick, and S. A. Duncan. 2015. “FGF2 Mediates Hepatic Progenitor Cell Formation During Human Pluripotent Stem Cell Differentiation by Inducing the WNT Antagonist NKD1”. Genes Dev 29: 2463-74.

Joshua Cruickshank

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Brendan Waters

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Aut quia assumenda deleniti facere cupiditate est ex. Et veritatis nihil dolores. Numquam exercitationem consequatur deserunt veritatis aut laudantium nemo. Quam molestias laudantium sequi culpa molestiae ad magni facilis. In sit consequatur ut mollitia qui labore occaecati cupiditate. Libero aut...

New 'off-the-shelf' stem cell CAR-T to be the basis of company born out of Boston Children’s Hospital and ElevateBio

News: August 04, 2022

By Max Bayer Aug 4, 2022 11:00am CAR-T ElevateBio Boston Children's Hospital Cell & Gene Therapy Just over a year after ElevateBio and Boston Children’s Hospital joined forces to develop new cell and gene therapies, the two are out with a new spinoff company and new data showing the promise of an...

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