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Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation.

Publication: Journal Article

Brazzo, Joseph A, John C Biber, Erik Nimmer, Yuna Heo, Linxuan Ying, Ruogang Zhao, Kwonmoo Lee, Matthias Krause, and Yongho Bae. 2021. “Mechanosensitive Expression of Lamellipodin Promotes Intracellular Stiffness, Cyclin Expression and Cell Proliferation.”. Journal of Cell Science 134 (12).

Global Optimization of Clusters in Gene Expression Data of DNA Microarrays by Deterministic Annealing.

Publication: Journal Article

Lee, Kwonmoo, Tae Su Chung, and Ju Han Kim. 2003. “Global Optimization of Clusters in Gene Expression Data of DNA Microarrays by Deterministic Annealing.”. Genomics & Informatics 1 (1): 20-24.

Self-Assembly of Filopodia-Like Structures on Supported Lipid Bilayers

Publication: Journal Article

Lee, Kwonmoo, Jennifer L. Gallop, Komal Rambani, and Marc W. Kirschner. 2010. “Self-Assembly of Filopodia-Like Structures on Supported Lipid Bilayers”. Science 329 (5997): 1341-45.

Hannah Wang is a third-year student at the Massachusetts Institute of Technology, majoring in Computation and Molecular Biology. She joined the Lee Lab in February 2025 and is currently working on using deep learning to analyze live cell movies and better understand breast cancer cells, with the...

A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation.

Publication: Journal Article

Vaidyanathan, Kalyanaraman, Chuangqi Wang, Amanda Krajnik, Yudong Yu, Moses Choi, Bolun Lin, Junbong Jang, et al. 2021. “A Machine Learning Pipeline Revealing Heterogeneous Responses to Drug Perturbations on Vascular Smooth Muscle Cell Spheroid Morphology and Formation.”. Scientific Reports 11 (1): 23285.

Ion transport and channel transition in biomembranes

Publication: Journal Article

Lee, Kwonmoo, and Wokyung Sung. 2002. “Ion Transport and Channel Transition in Biomembranes”. Physica A: Statistical Mechanics and Its Applications 315 (1): 79-97.

A Stochastic Model of Conductance Transitions in Voltage-Gated IonChannels

Publication: Journal Article

Lee, Kwonmoo, and Wokyung Sung. 2002. “A Stochastic Model of Conductance Transitions in Voltage-Gated IonChannels”. Journal of Biological Physics 28 (2): 279-88.

Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.

Publication: Journal Article

Lee, Kwonmoo, Hunter L Elliott, Youbean Oak, Chih-Te Zee, Alex Groisman, Jessica D Tytell, and Gaudenz Danuser. 2015. “Functional Hierarchy of Redundant Actin Assembly Factors Revealed by Fine-Grained Registration of Intrinsic Image Fluctuations.”. Cell Systems 1 (1): 37-50.

Emerging machine learning approaches to phenotyping cellular motility and morphodynamics

Publication: Journal Article

Choi, Hee June, Chuangqi Wang, Xiang Pan, Junbong Jang, Mengzhi Cao, Joseph A Brazzo, Yongho Bae, and Kwonmoo Lee. 2021. “Emerging Machine Learning Approaches to Phenotyping Cellular Motility and Morphodynamics”. Physical Biology 18 (4): 041001.