Search

Infantile hemangioma is a vascular tumor that can grow rapidly, causing organ damage, disfigurement and morbidity. My lab has focused on the cellular mechanisms that drive this uncontrolled vascular growth. We isolated increasingly less differentiated cells from hemangioma tissue (see figure), which...

Overview Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases. We have three main areas: (1) vascular tumors (infantile hemangioma) and (2)vascular malformations (e.g., capillary malformation), (3) endothelial to mesenchymal transition (EndMT) in...

We study endothelial plasticity in cardiac valves and how this relates to the ability of valves to adapt to both normal and pathologic events. We showed that valve endothelial cells (VECs) from aortic, pulmonic and mitral valves can recapitulate processes that occur during valve development - e.g...

Joyce Bischoff, PhD Principle Investigator Joyce Bischoff received an A.B. in chemistry from Duke University and a Ph.D. in biochemistry from the Washington University School of Medicine. She was a post-doctoral fellow at the Whitehead Institute for Biomedical Research. She joined the Surgical...