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Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7

Publication: Journal Article

C*, Ren, Smith SG*, Yap KL, Li S, Li J, Mezei M, Vincek AS, Aguilo F, Walsh MJ, and Zhou MM. 2016. “Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7”. ACS Medicinal Chemistry Letters 7 (6): 601-5.

MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cells

Publication: Journal Article

K, Jiang, Ren C, and Nair VD. 2013. “MicroRNA-137 Represses Klf4 and Tbx3 During Differentiation of Mouse Embryonic Stem Cells”. Stem Cell Research 11 (3): 1299-1313.

Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation

Publication: Journal Article

KL, Cheung, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, et al. 2017. “Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation”. Molecular Cell 65 (6): 1068-1080.e5.

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Publication: Journal Article

C*, Ren, Zhang G*, Han F, Fu S, Cao Y, Zhang F, Zhang Q, et al. 2018. “Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth”. Proceedings of the National Academy of Sciences of the United States of America 115 (31): 7949-54.

Strategies of Core Value Assessment for Innovative Pharmaceutical Projects 创新医药项目核心价值评估策略

Publication: Journal Article

H, Wu, and Ren C. 2018. “Strategies of Core Value Assessment for Innovative Pharmaceutical Projects 创新医药项目核心价值评估策略”. Progress in Pharmaceutical Sciences 药学进展 42 (2): 141-47.

Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain

Publication: Journal Article

C, Ren, Zeng L, and Zhou MM. 2016. “Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain”. Methods in Enzymology 573: 321–343.

Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data

Publication: Journal Article

F*, Zhang, Ren C*, Zhao H, Yang L, Su F, Zhou MM, Han J, Sobie EA, and Walsh MJ. 2016. “Identification of Novel Prognostic Indicators for Triple-Negative Breast Cancer Patients through Integrative Analysis of Cancer Genomics Data and Protein Interactome Data”. Oncotarget 7 (44): 71620-34.

CV

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PhD, Mount Sinai School of Medicine MS, Chinese Academy of Sciences BS, Nankai University

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain

Publication: Journal Article

C, Ren, Morohashi K, Plotnikov AN, Jakoncic J, Smith SG, Li J, Zeng L, et al. 2015. “Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain”. Chemistry & Biology 2 (22): 161-68.

Extraction and identification of collagen-derived peptides with hematopoietic activity from Colla Corii Asini

Publication: Journal Article

H, Wu, Ren C, Yang F, Qin Y, Zhang Y, and Liu J. 2016. “Extraction and Identification of Collagen-Derived Peptides With Hematopoietic Activity from Colla Corii Asini”. Journal of Ethnopharmacology 182: 129-36.