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Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7

Publication: Journal Article

C*, Ren, Smith SG*, Yap KL, Li S, Li J, Mezei M, Vincek AS, Aguilo F, Walsh MJ, and Zhou MM. 2016. “Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7”. ACS Medicinal Chemistry Letters 7 (6): 601-5.

CV

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MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cells

Publication: Journal Article

K, Jiang, Ren C, and Nair VD. 2013. “MicroRNA-137 Represses Klf4 and Tbx3 During Differentiation of Mouse Embryonic Stem Cells”. Stem Cell Research 11 (3): 1299-1313.

Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation

Publication: Journal Article

KL, Cheung, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, et al. 2017. “Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation”. Molecular Cell 65 (6): 1068-1080.e5.

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Publication: Journal Article

C*, Ren, Zhang G*, Han F, Fu S, Cao Y, Zhang F, Zhang Q, et al. 2018. “Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth”. Proceedings of the National Academy of Sciences of the United States of America 115 (31): 7949-54.

Strategies of Core Value Assessment for Innovative Pharmaceutical Projects 创新医药项目核心价值评估策略

Publication: Journal Article

H, Wu, and Ren C. 2018. “Strategies of Core Value Assessment for Innovative Pharmaceutical Projects 创新医药项目核心价值评估策略”. Progress in Pharmaceutical Sciences 药学进展 42 (2): 141-47.

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

Publication: Journal Article

F, Sher, Hossain M, Seruggia D, Schoonenberg VAC, Yao Q, Cifani P, Dassama LMK, et al. 2019. “Rational Targeting of a NuRD Subcomplex Guided by Comprehensive in Situ Mutagenesis”. Nature Genetics 51 (7): 1149-59.

Chunyan Ren

Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain

Publication: Journal Article

C, Ren, Zeng L, and Zhou MM. 2016. “Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain”. Methods in Enzymology 573: 321–343.

Direct interaction of DNMT inhibitors to PrPC suppresses pathogenic process of prion

Publication: Journal Article

DH, Kim, Ren C, Ryou C, and Li J. 2019. “Direct Interaction of DNMT Inhibitors to PrPC Suppresses Pathogenic Process of Prion”. Acta Pharmaceutica Sinica B.