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A 25 year-old patient with a Port-a-Cath implanted in the right chest complains of sudden onset severe neck pain and headaches with flushing central line and PN infusions. Labs and exam normal, including afebrile. Previous X-ray shows central line tip in at the cavo-atrial junction. Today, chest X...

Appreciate the contributions of the following and others to the website's content: Alexandra Carey, MD Daniel Kamin, MD Jennifer McClelland, FNP-BC Carolyn Rosa, CPNP-BC Mary Gallotto, BSN Melissa Takvorian-Bene, BSN Megan Gray, RD Ana Arena, RD Christina Tascione, BA Kathleen Gura, PharmD Margaret...

Overview Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases. We have three main areas: (1) vascular tumors (infantile hemangioma) and (2)vascular malformations (e.g., capillary malformation), (3) endothelial to mesenchymal transition (EndMT) in...

We study endothelial plasticity in cardiac valves and how this relates to the ability of valves to adapt to both normal and pathologic events. We showed that valve endothelial cells (VECs) from aortic, pulmonic and mitral valves can recapitulate processes that occur during valve development - e.g...

Joyce Bischoff, PhD Principle Investigator Joyce Bischoff received an A.B. in chemistry from Duke University and a Ph.D. in biochemistry from the Washington University School of Medicine. She was a post-doctoral fellow at the Whitehead Institute for Biomedical Research. She joined the Surgical...

Summa Cum Laude Merit Award ISMRM 2019 Society of Pediatric Radiology Multi-institutional Research Award 2019 Harvard and Boston Children's Hospital Translationa Research Program Award 2019 Caffey Award- Best Science Paper at Society of Pediatric Radiology Meeting in Nashville, May 2018 Feed and...

PhD, Mount Sinai School of Medicine, New York, USA MS, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China BS, Nankai University, Tianjin, China

Caregiver flushes the central venous catheter and they feel an unusual amount resistance to flushing. The catheter has the following appearance (see photo below). They call HPN on-call for advice. What is the first thing you should advise family to do? A. Offer reassurance if central line is not...