Endocytic Adaptors in Cardiovascular Disease
Cui, Kui, Yunzhou Dong, Beibei Wang, Douglas B Cowan, Siu-Lung Chan, John Shyy, and Hong Chen. 2020. “Endocytic Adaptors in Cardiovascular Disease”. Frontiers in Cell and Developmental Biology 8: 624159.
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Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development
Chang, Baojun, Kandice L Tessneer, John McManus, Xiaolei Liu, Scott Hahn, Satish Pasula, Hao Wu, et al. 2015. “Epsin Is Required for Dishevelled Stability and Wnt Signalling Activation in Colon Cancer Development”. Nature Communications 6: 6380.
Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity.
Nemoto, Y, B G Kearns, M R Wenk, H Chen, K Mori, J G Alb, P De Camilli, and V A Bankaitis. 2000. “Functional Characterization of a Mammalian Sac1 and Mutants Exhibiting Substrate-Specific Defects in Phosphoinositide Phosphatase Activity.”. The Journal of Biological Chemistry 275 (44): 34293-305.
The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.
Rosenthal, J A, H Chen, V I Slepnev, L Pellegrini, A E Salcini, P P Di Fiore, and P De Camilli. 1999. “The Epsins Define a Family of Proteins That Interact With Components of the Clathrin Coat and Contain a New Protein Module.”. The Journal of Biological Chemistry 274 (48): 33959-65.
Epsins oversee smooth muscle cell reprograming by influencing master regulators KLF4 and OCT4
Wang, Beibei, Kui Cui, Bo Zhu, Yunzhou Dong, Donghai Wang, Bandana Singh, Hao Wu, et al. 2024. “Epsins Oversee Smooth Muscle Cell Reprograming by Influencing Master Regulators KLF4 and OCT4”. BioRxiv 2024.01.08.574714.
Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis through Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9-Mediated Low-density Lipoprotein Receptor Degradation
Zhu, Bo, Krishan Gupta, Kui Cui, Beibei Wang, Marina V. Malovitchko, Kathryn S. Li, Hao Wu, et al. 2024. “Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis through Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9-Mediated Low-Density Lipoprotein Receptor Degradation”. BioRxiv 2024.08.26.609742.
Epsin Mimetic UPI Peptide Delivery Strategies to Improve Endothelization of Vascular Grafts
Changizi, Shirin, Mahyar Sameti, Gabrielle L Bazemore, Hong Chen, and Chris A Bashur. 2023. “Epsin Mimetic UPI Peptide Delivery Strategies to Improve Endothelization of Vascular Grafts”. Macromolecular Bioscience 23 (9): e2300073.
Low RNA stability signifies increased post-transcriptional regulation of cell identity genes
Li, Yanqiang, Yang Yi, Jie Lv, Xinlei Gao, Yang Yu, Sahana Suresh Babu, Ivone Bruno, et al. 2023. “Low RNA Stability Signifies Increased Post-Transcriptional Regulation of Cell Identity Genes”. Nucleic Acids Research 51 (12): 6020-38.
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation
Chen, Jiyuan, Marisela Rodriguez, Jinrui Miao, Jing Liao, Pritesh P Jain, Manjia Zhao, Tengteng Zhao, et al. 2022. “Mechanosensitive Channel Piezo1 Is Required for Pulmonary Artery Smooth Muscle Cell Proliferation”. American Journal of Physiology: Lung Cellular and Molecular Physiology 322 (5): L737-L760.
Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling
Dong, Yunzhou, Beibei Wang, Kui Cui, Xiaofeng Cai, Sudarshan Bhattacharjee, Scott Wong, Douglas B Cowan, and Hong Chen. 2021. “Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling”. Cells 10 (8).