Safety of enteral nutrition practices in neonates with umbilical arterial catheters in situ: current evidence to guide clinical practice.

Lima, G., Morton, S. U., Hair, A. B., Good, M., Weems, M., Crocker, C. E., Denning, P., Yazawa, E., Pavlek, L., Pallotto, E., Staines, L., Cortezzo, D., Lakshminrusimha, S., Ibrahim, J., & Levy, P. T. (2025). Safety of enteral nutrition practices in neonates with umbilical arterial catheters in situ: current evidence to guide clinical practice.. Journal of Perinatology : Official Journal of the California Perinatal Association.

Abstract

Umbilical arterial catheters (UAC) in neonates are used for blood pressure monitoring, blood sampling, administration of fluids, nutrition, and medications. As UAC applications evolve, enteral nutrition practices vary in neonates in the presence of a UAC. The theoretical concern for mesenteric ischemia when a UAC is in place led to early nil per os approaches, delaying the initiation of enteral nutrition. More contemporary practices have favored introducing enteral feeding in neonates with UACs. However, there remains a paucity of data to guide clinical practice approaches regarding enteral feeding in neonates with a UAC in place. In this perspective article, we examine the physiological effects of UACs and review existing literature on feeding practices in neonates with a UAC. We offer an approach to managing enteral feeding in neonates with a UAC, addressing the central question: Is routine feeding in neonates with a UAC in place justified in current clinical practice?

Last updated on 11/25/2025
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