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Physical Diagnosis Findings with Central Venous Catheters

Central Venous Catheter cuff exposed The central venous catheter dacron cuff is supposed to be underneath the skin, so it can hold the catheter firmly within tunnel. Here we see the catheter malpositioned with the dacron cuff externalized. Purulent discharge from CVC exit site Cellulitis around...

Hla Lab Alumni

Name (Instutition and duration with Dr. Hla) Current Appointment Past Postdoctoral Trainees Ari Ristimaki, M.D., Ph.D. GI Pathologist and Professor, Helsinki University, Finland Menq-Jer Lee, Ph.D. Retired Pazit Ben-Av, Ph.D. Research Scientist, Weizmann Institute, Israel Shobha Thangada, Ph.D...

Regulation and Function of S1P Receptors

There are five high-affinity G protein-coupled receptors (GPCR) for S1P, termed as S1PR1-5. In the figure shown below, activation of S1PR1 by chaperone-bound S1P is schematically represented. Most cells express one or more subtypes of S1PRs. S1PR1 is abundantly expressed in the vascular endothelium...