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A Screen Using iPSC-Derived Hepatocytes Reveals NAD(+) as a Potential Treatment for mtDNA Depletion Syndrome

Publication: Journal Article

Jing, R., J. L. Corbett, J. Cai, G. C. Beeson, C. C. Beeson, S. S. Chan, D. P. Dimmock, et al. 2018. “A Screen Using IPSC-Derived Hepatocytes Reveals NAD(+) As a Potential Treatment for MtDNA Depletion Syndrome”. Cell Rep 25: 1469-1484 e5.

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Ready-made CAR T Cells

News: August 04, 2022

New method could allow scaled-up production of generic cells for cancer immunotherapies By NANCY FLIESLER | Boston Children’s August 4, 2022 Research 3 min read Killer T cells (green and red) surround a cancer cell (blue, center). Image: Alex Ritter, Jennifer Lippincott Schwartz, and Gillian...

Tiki proteins are glycosylphosphatidylinositol-anchored proteases.

Publication: Journal Article

Li, Mingyi, Jing Zheng, Xi He, and Xinjun Zhang. 2022. “Tiki Proteins Are Glycosylphosphatidylinositol-Anchored Proteases.”. FEBS Letters 596 (8): 1037-46.

Kern Faculty Leadership Fellows 2025 - 2026

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2024 Publications by DON Faculty

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Ran Jing, Ph.D. - Boston Children's Hospital/Harvard Medical School

Dr. Ran Jing is a stem cell biologist and immunologist at Harvard Medical School and Boston Children's Hospital. Dr. Jing's research focuses on decoding the intricacies of lymphoid development using innovative models like iPSC-derived T and NK cells. Concurrently, we employ cell engineering, regenerative medicine, and synthetic biology to create off-the-shelf CAR T cell immunotherapies for cancer and autoimmune diseases.

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia

Publication: Journal Article

Cayo, M. A., S. K. Mallanna, F. Di Furio, R. Jing, L. B. Tolliver, M. Bures, A. Urick, et al. 2017. “A Drug Screen Using Human IPSC-Derived Hepatocyte-Like Cells Reveals Cardiac Glycosides As a Potential Treatment for Hypercholesterolemia”. Cell Stem Cell 20: 478-489 e5.