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HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II

Publication: Journal Article

DeLaForest, A., F. Di Furio, R. Jing, A. Ludwig-Kubinski, K. Twaroski, A. Urick, K. Pulakanti, S. Rao, and S. A. Duncan. 2018. “HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human IPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II”. Genes (Basel) 10.

A small-molecule screen reveals that HSP90beta promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover

Publication: Journal Article

Jing, R., C. B. Duncan, and S. A. Duncan. 2017. “A Small-Molecule Screen Reveals That HSP90beta Promotes the Conversion of Induced Pluripotent Stem Cell-Derived Endoderm to a Hepatic Fate and Regulates HNF4A Turnover”. Development 144: 1764-74.

DKK1 is a strong candidate for mesiodens and taurodontism.

Publication: Journal Article

Kantaputra, Piranit, Peeranat Jatooratthawichot, Naomi Kottege, Robert P Anthonappa, Massupa Kaewgahya, Sissades Tongsima, Chumpol Ngamphiw, James R Ketudat Cairns, Danilo Predes, and Xi He. 2023. “DKK1 Is a Strong Candidate for Mesiodens and Taurodontism.”. Clinical Genetics 103 (6): 714-16.

CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development

Publication: Journal Article

da Rocha, Lummertz, C. Kubaczka, W. W. Sugden, M. A. Najia, R. Jing, A. Markel, Z. C. LeBlanc, et al. 2022. “CellComm Infers Cellular Crosstalk That Drives Haematopoietic Stem and Progenitor Cell Development”. Nat Cell Biol 24: 579-89.

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Layla Cronin

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Dr. Ran Jing receives the Pathway to Independence Award from the NHLBI

News: September 13, 2023

Congrats to Dr. Ran Jing on receiving the Pathway to Independence Award from the NHLBI. This grant will support his research on human pluripotent stem cells to study lymphoid development & generate PSC-derived T cells for off-the-shelf adoptive T cell therapies.

Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.

Publication: Journal Article

Zheng, Shaoqin, Jiahui Lin, Zhongqiu Pang, Hui Zhang, Yinuo Wang, Lanjing Ma, Haijiao Zhang, et al. 2022. “Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.”. Advanced Science (Weinheim, Baden-Wurttemberg, Germany) 9 (28): e2200750.

Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing

Publication: Journal Article

Bhattacharjee, Sudarshan, Jianing Gao, Yao Wei Lu, Shahram Eisa-Beygi, Hao Wu, Kathryn S. Li, Amy E. Birsner, et al. 2024. “Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing”. BioRxiv 2024.02.07.579019.

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