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HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II

Publication: Journal Article

DeLaForest, A., F. Di Furio, R. Jing, A. Ludwig-Kubinski, K. Twaroski, A. Urick, K. Pulakanti, S. Rao, and S. A. Duncan. 2018. “HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human IPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II”. Genes (Basel) 10.

A small-molecule screen reveals that HSP90beta promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover

Publication: Journal Article

Jing, R., C. B. Duncan, and S. A. Duncan. 2017. “A Small-Molecule Screen Reveals That HSP90beta Promotes the Conversion of Induced Pluripotent Stem Cell-Derived Endoderm to a Hepatic Fate and Regulates HNF4A Turnover”. Development 144: 1764-74.

CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development

Publication: Journal Article

da Rocha, Lummertz, C. Kubaczka, W. W. Sugden, M. A. Najia, R. Jing, A. Markel, Z. C. LeBlanc, et al. 2022. “CellComm Infers Cellular Crosstalk That Drives Haematopoietic Stem and Progenitor Cell Development”. Nat Cell Biol 24: 579-89.

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Dr. Ran Jing receives the Pathway to Independence Award from the NHLBI

News: September 13, 2023

Congrats to Dr. Ran Jing on receiving the Pathway to Independence Award from the NHLBI. This grant will support his research on human pluripotent stem cells to study lymphoid development & generate PSC-derived T cells for off-the-shelf adoptive T cell therapies.

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A Screen Using iPSC-Derived Hepatocytes Reveals NAD(+) as a Potential Treatment for mtDNA Depletion Syndrome

Publication: Journal Article

Jing, R., J. L. Corbett, J. Cai, G. C. Beeson, C. C. Beeson, S. S. Chan, D. P. Dimmock, et al. 2018. “A Screen Using IPSC-Derived Hepatocytes Reveals NAD(+) As a Potential Treatment for MtDNA Depletion Syndrome”. Cell Rep 25: 1469-1484 e5.

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Brook Heathcote

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HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II

A small-molecule screen reveals that HSP90beta promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover

CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development

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Layla Cronin

Dr. Ran Jing receives the Pathway to Independence Award from the NHLBI

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A Screen Using iPSC-Derived Hepatocytes Reveals NAD(+) as a Potential Treatment for mtDNA Depletion Syndrome

Research

Brook Heathcote